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The history of department
In 1979, the Department of Oncology was organized on the basis of the Tselinograd regional oncology dispensary. The first head of the department was a professor, d.m.s. Volobuev N.A. Assoc. Shabash E.G., Assistant Ph.D. Struzhko I.B., Ph.D. Zadontseva N.S. (oncogynecologist), Assistant sub-Shivalov B.V., Daniyarov S.O.
From 1991 to 1994, the Department of Oncology was headed by an assistant professor, Ph.D. Zarkeshev S.R., as part of the department, the assistants of K.M.N. Verchenko V.V., Zhukov Yu.V. From 1995 to 1997, the department was reorganized in the course of oncology with radiation diagnostics and radiation therapy: the head worked on the course. Course, Associate Professor, Ph.D. Letnikova L.S., Associate Professor, Ph.D. Volikov O.Yu., assistants, Podshivalov B.V., Zhakipbaev K.A., Nasov G.A.
In 1997, the Department of Oncology was again organized (head of prof.,dms Makishev A.K., a graduate of the Tselinograd Medical Institute, the city of Tselinograd, a student of professor, dms Davydov , President of the Academy of Medical Sciences of Russia, Academician of the Academy of Sciences of Russia, General Director of the Oncological Scientific Center of the RAMS named after N.N. Blokhin, Moscow) with a course of radiation diagnostics and radiation therapy (head of the course of associate professor, Ph.D., Sumlokova L. FROM.). The Department of Oncology is working as associates, Ph.D. Zhakipbaev K.A., Ph.D. Mukametzhan K.K., Ph.D. Zhagiparov M.K., Ph.D. Kenbaeva D.K. Since 2000, the department included the courses of endocrinology, medical nutrition and vocatologies (head of the course of associate professor, Ph.D. Ibra-va M.T.), Assistants of K.M.N. Sadybekova G.T., assistants Temirbaeva S.T. and Zelenskaya V.N. Since 2005, the department includes a course of ptisies (head of the course of Associate Professor, Ph.D. Bugakov A.A.), Associate Professor, Ph.D. Bugakova S.L., Assistants Association G.N., Zhandarkulov A.A., Rakhimzha-Nova R.S. Since 2006, the department includes a course of neurosurgery (head of the course of professor, d.m.s. Akshulakov S.K.).
During the existence of the department, the clinical residency, graduate school and residency at the Department of Oncology graduated from Mashkova O.N., Ushakov S.A., Vlasov I.K., Zhagiparov M.K., Zhusupova B.T., Dibaeva E.R., Sultanov R.R., Imanbaev H.A., Saktashev B.Sh., Stefanov I.I., Mauletbaev M.S., Suenshbaeva G.T., Sarsenbaeva A.M., AMANDOSOVA A.N., Manasheva A. S., Turebekova A.G., Ermaganbetova A.T., Aripzhanova G.O., Bagatova G.B., Tazhikova A.M., Bokebaeva A.Sh., Abilova L.G., Timchenko N.S. , Kule-Shova L.A., Aitbaeva A.A., Zauyrbekova A.S., Kukanova A.M., Muratkalieva Zh.K., Khashimova L.A., Dzantemirova N.M., Dolda S., Chief Z.S., Zhamantaeva A.S., Dzhumabaeva G.T., Abdurakhmanov F.U., Zharkeneva MB, Sagieva S.B., Niyazbaeva E.A., Aliyeva G.N., Moldantaeva A. K., Danyarova A.A., Yugay V.A., Bolatova Sh.E., Sovekhanova M.M., Nigmatulla D., Suleimenova A.P., Zhumadilova A., Kuralbaev Zh.
Activity
Currently, the department is studying under undergraduate, internships, residency, magistracy and doctoral studies. The department is provided with a sufficient number of staff including professors, associate professors and assistants. The Department of Oncology supports the principle of continuity, so most graduates of the Department of Oncology are currently its employees. Every year, the staff of the Department of Oncology is replenished from among the employees of the “multidisciplinary medical center” of the Akimat Nur Sultan, who are mentors for oncologists. In the educational process, innovative training technologies are actively used, such as the method of reference signals, CASE-Study, PBL, CBL. The use of the standard of the standardized patient allows you to imitate the real clinical situation for the examination of students, interns and residents. To this end, 25 acts of new educational technologies have been developed and implemented in the educational process, which cover all topics of the calendar-thematic plan. Annually, educational and methodological manuals for students and interns are published such as “oncogynecology” in the Kazakh language, “mastopathy and breast cancer”, “malignant and benign diseases of the stomach”, “oncogynecology”, “Oncological gynecology” in English. The assistants of the Department of Oncology, having an existing IELTS certificate, conduct classes in English in groups with foreign students from India and Pakistan. Regularly, the teaching staff improves pedagogical qualifications with cascading involvement of all employees of the department. As well as employees of the Department of Oncology, they relate the training programs for innovative teaching methods of the faculty of medical universities in the Republic of Kazakhstan and nearby countries in the framework of academic mobility (Kazakh National Medical University named after S. D. Aspendiyarova, Tajik State Medical University named after Abuali Ibni Sino, Tashkent Pediatric Medical Institute).
Over the entire period of activity, more than 50,000 students who work in all regions of Kazakhstan and abroad have received knowledge at the Department of Oncology. The Department of Oncology implements postgraduate education in residency with a degree in oncology (adult). Given the requests of practical healthcare, the Department of Oncology under the leadership of Professor Makishev A.K. Provides the northern regions of the country. In 2022-2023, the number of residents studying at the Department of Oncology is 45 students. Over the entire period of the department, the release of residents amounted to more than 65 oncologists.
Together with the Republican State Enterprise “National Center for Biotechnology of the Republic of Kazakhstan”, for the first time in Kazakhstan, scientific work is being carried out related to the provision of tumor cells and human tissues within the framework of the state program “Development of modern technologies for the formation of a biotechnology cluster in the Republic of Kazakhstan”. Development of a method for the use of MCA (monoclonal antibodies) in the diagnosis of oncological diseases. Currently, work is underway to study the immunobiological properties of the obtained antigens - immunization of mice to determine the immunogenicity of the obtained antigens.
Together with the PI "National Laboratory Astana" at the AEO "Nazarbayev University" research work is being carried out, a grant from the Ministry of Education and Science of the Republic of Kazakhstan "Development of pancreatic cancer therapy with an oxidative combination of drugs targeting cancer cells-mutants KRAS" and targeted funding programs "Development of antitumor drugs that induce glucose-dependent cytotoxic oxidative stress.
Reconstructive methods for the treatment of breast cancer (TRAM-flap, DIEP-flap) are being introduced.
Work continues on the study and implementation of the possibilities of oncological rehabilitation of oncological patients with complications after complex treatment.
The staff of the Department of Oncology is actively publishing the results of scientific research in international journals included in the Scopus and Web of science databases, in journals recommended by KKSON, in collections of abstracts of international conferences. The results of the research work are confirmed by fifteen certificates of intellectual property copyright.
The average Hirsch index of the teaching staff is 1.
The number of articles in journals indexed in Web of Science and Scopus is 9, of which:
➢ in journals of the first quartile Q1- 2 articles
➢ in journals of the first quartile Q2 - 2 articles
➢ in journals of the first quartile Q3 - 3 articles
➢ in journals of the first quartile Q4 - 2 articles
Under the guidance of Professor Makishev A.K., the publication work of undergraduates and doctoral students is monitored by the chairman of the council of undergraduates and doctorates of the Department of Oncology, editor-in-chief and founder of the Journal of Oncology and Immunology Research Azhken Bakhtiyar Talgatovich.
The doctoral dissertation was defended at the Department of Oncology:
Prof. Makishev A.K., 1997
4 candidate dissertations were defended at the Department of Oncology:
1. Zhakipbaev K.A., 1999
2. Zhagiparov M.K., 2006
3. Saktashev, B.Sh., 2010
4. Imanbaev Kh.A., 2010
Since 2016, 11 master's theses have been defended:
1. Dzhandaev D.S.
2. Shtefanov I.I.
3. Bekisheva A.T.
4. Aitbaeva A.A.
5. Ermagambetova A.T.
6. Kukanova A.M.
7. Rutzhanuly I.
8. Tazhikova A.M.
9. Amandosova A.N.
10. Omarov E.D.
11. Dzhantemirova N.M.
Currently studying for a master's degree:
1) Azhken B.T.
2) Madinova M.B.
In 2022, 2 doctoral dissertations (PhD) were defended in the specialty "Medicine" in the areas of rehabilitation of patients after surgical treatment of cancer of the gastrointestinal tract and surgical treatment of patients with locally advanced forms of tumors of the abdominal cavity and retroperitoneal space.
1) Bekisheva A.T.
2) Mauletbaev M.S.
Planned defense of doctoral dissertations in the specialty "Medicine":
1) Shtefanov I.I.
2) Akhmedin D.N.
Currently studying in (PhD) doctoral studies:
1) Tazhikova A.M.
2) Kukanova A.M.
3) Dzhantemirova N.M.
Patents for inventions have been received, rationalization proposals have been made, more than 550 scientific publications and theses have been published. The staff of the department took an active part in the work of thirteen International Congresses of Oncologists and Radiologists of the CIS and Eurasia countries, presented 5 reports, 3 poster reports, 56 scientific abstracts were published at the International Congress of European Oncologists (Sweden, Stockholm, 2008).
Employees take a permanent part in the annual congresses of oncologists and radiologists of the CIS and Eurasian countries. Active participation in international scientific and practical conferences organized by the Nur-Sultan Multidisciplinary Medical Center. Participation of employees in the form of reports and publications at congresses of oncologists and radiologists with international participation.
Assistants, residents, undergraduates and doctoral students of the department are actively involved in speaking at conferences of young scientists. Recently, prizes have been awarded to:
Kukanova A.M. "Uterine artery chemoembolization in patients with cervical cancer". 1st place, 2015
Dzhantemirova N.M. "Features of metastatic lesions of axillary lymph nodes in breast cancer" 1st place, 2016
Bekisheva A.T. "Possibilities of treatment of dumping syndrome in patients with surgical treatment of gastric cancer". 1st place, 2017
Zharkeneva M.B. "Peculiarities of surgical treatment of patients with kidney cancer complicated by thrombosis of the inferior vena cava" Diploma of the participant, 2018
Mauletbaev M.S. "Repeated operations for tumors of the abdominal cavity and retroperitoneal space after exploratory laparotomy" 1st place, 2018
Madinova M.B. "Peculiarities of MOHS micrographic surgery for skin cancer" 1st place, 2021
Amangeldina A.A. "Dynamic follow-up of patients with PLA after surgical treatment" 2nd place, 2021
Bogaychuk A.A. "The importance of IHC research in breast cancer therapy" 3rd place, 2021
Gazizova E.B. "Fluorescent diagnostics of sentinel lymph nodes in stage I-II oral cavity cancer" Diploma of the participant, 2021.
3. Clinical activities.
Over the past 25 years, in the clinic of the GKP on the REM "Multipurpose Medical Center" of the Akimat of the city of Nur-Sultan, the staff of the department and dispensary under the guidance of the head. Department of Professor Makishev A.K. For the first time, modern methods of diagnosis and surgical treatment of malignant neoplasms were introduced using extended-combined surgical interventions with lymph node dissection:
• in case of cancer of the esophagus, stomach, cardioesophageal zone and post-burn cicatricial stenosis of the esophagus - simultaneous extended extirpation and subtotal resection of the thoracic and abdominal esophagus with esophagogastroplasty (Lewis, Savinykh and Garlock type operation), extended-combined gastrectomy, subtotal proximal and distal resection of the stomach, simultaneous extirpation of the esophagus with plasty with an isoperistaltic gastric stalk and the whole stomach;
• for lung cancer – extended pulmonectomy, bilobectomy, lobectomy with intrapericardial ligation of pulmonary vessels;
• cancer of the larynx - extended extirpation of the larynx with lymph node dissection according to Crile;
• in case of pancreatic cancer - gastropancreatoduodenal resection, total pancreatectomy, corporocaudal resection of the pancreas;
• in case of liver cancer – hemihepatectomy, liver resection;
• in cancer of the rectum - abdomino-anal resection of the rectum with bringing down the sigmoid colon;
• for kidney cancer - extended nephrectomy with resection and plasty of the inferior vena cava and removal of a metastatic thrombus from its lumen, wedge-shaped resection of the kidney;
• in case of bladder cancer - simultaneous extirpation of the bladder with the creation of a urinary reservoir from a segment of the small intestine and transplantation of the ureters into it (Brikker's operation);
• in prostate cancer - radical prostatectomy.
• with cancer of the body and cervix (extended extirpation of the uterus with pelvic-iliac lymph node dissection according to Wertheim).
For the first time, the most complex operations on the skeletal system were performed - resections of bone tumors (sternum, ilium, femur) with replacement of the defect with bone cement, on the organs of the head and neck (resection of the larynx, maxillary sinus), laparothoracoscopic endovideosurgical operations on the organs of the chest and abdominal cavities (removal lung tumors, tumors of the female genital organs).
For the first time in 2009, the staff of the Department of Oncology together with the staff of the oncological dispensary in Astana held an international meeting and master classes with leading professors of the Medical Faculty of Harvard University in Boston, USA. Patients of the surgical, oncogynecological, radiological and chemotherapeutic departments were consulted together, a number of joint operations were performed, lectures were given.
4. Educational work.
The composition of the department actively participates in the celebration of the "Independence Day of the Republic of Kazakhstan". Reports are being prepared dedicated to the "Independence Day of the Republic of Kazakhstan" for students, residents and doctors - interns of 6-7 courses. Employees take an active joint part in the celebration of the "New Year", "March 8" and "Nauryz Meiramy", organized by the trade union and the administration of NJSC "MUA". Every year the department during the celebration of "Nauryz Meiramy" takes first place in the nominations. Actively participate in the sports life of the university. In the "Rector's Cup" in chess, organized by the administration of NJSC "MUA", in volleyball in "Togyz kumalak", in checkers and tennis competitions, they take prizes.
Celebrate the anniversary of the victory of the Soviet people over the Nazi troops. With students and interns, the Day of Remembrance of the heroes of Kazakhstan - participants in the Second World War is held with a report dedicated to this day.
According to the plan of educational work of the Department of Oncology, career guidance work is being carried out at school-lyceum No. 38 in Nur-Sultan. During the orientation work, slides and videos are used that tell about the activities of the medical university.
Achievements
Patents for inventions have been received, rationalization proposals have been made, more than 550 scientific publications and theses have been published. The staff of the department took an active part in the work of ten International Congresses of Oncologists and Radiologists of the CIS countries, presented oral and poster reports, more than 500 scientific abstracts have been published.
Contacts
Astana, 17 Manas street. "Multidisciplinary medical center" of city administration of Astana.
Phonenumber of the Department: 54-20-08.
E-mail: kafedra.onkologii.amu@gmail.com
